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INTEGRATED DRUG DISCOVERY

Integrating Functional Biology and Medicinal Chemistry for the Development of Novel Pharmaceuticals

Tranzyme Pharma’s proprietary technologies in medicinal chemistry and functional biology enable a powerful, integrated strategy for the discovery and development of new pharmaceutical products. These technologies are applicable to a broad range of targets, including two of the most relevant classes for pharmaceutical development, G protein-coupled receptors (GPCRs) and protein kinases. This combination of chemistry and biology provides competitive advantages to accelerate drug discovery and development.



  MATCH™ - Macrocyclic Template Chemistry

Robust synthetic methods for rapid hit-to-clinic optimization of the Company's macrocyclic small molecules.

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  HitCREATE™ Library

A library of over 25,000 distinct macrocyclic small molecules that captures diverse spatial topology and functionality.

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  TExT™ - TranzExpression Technology

Introduction of functional biology capabilities in all phases of the drug discovery process though high-content screening, assay development, and animal models of disease.

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