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PRESS RELEASE

Tranzyme Pharma to Present at the 26th Annual JPMorgan Healthcare Conference




RESEARCH TRIANGLE PARK, N.C. and SHERBROOKE, Québec (December 19, 2007) Tranzyme Pharma, a leading biopharmaceutical company developing small molecule drugs for the treatment of gastrointestinal (GI) and metabolic diseases, announced today that Vipin K. Garg, Ph.D., President and CEO, will present at the upcoming 26th Annual JPMorgan Healthcare Conference being held from January 7-10, 2008. Tranzyme’s presentation will take place on Monday, January 7, 2008 at 3:30 p.m. PST at the Westin St. Francis Hotel in San Francisco, CA.

Dr. Garg will provide a corporate overview and an update on the two ongoing Phase IIb clinical trials of Tranzyme’s lead product, TZP-101, an intravenous ghrelin agonist being investigated for the treatment of severe gastroparesis and post-operative ileus. In July 2007, the FDA granted TZP-101 fast-track designation for severe gastroparesis.